ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines.
- Creator: Lozinski, Mathew , Bowden, Nikola A. , Graves, Moira C. , Fay, Michael , Day, Bryan W. , Stringer, Brett W. , Tooney, Paul A.
- Resource Type: journal article
- Date: 2024
Bladder cancer survival in patients with NOD2 or CDKN2A variants
- Creator: Złowocka-Perłowska, Elżbieta , van de Wetering, Thierry , Tołoczko-Grabarek, Aleksandra , Scott, Rodney J. , Lubiński, Jan
- Resource Type: journal article
- Date: 2022
ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration.
- Creator: Ding, Jingyu , Zhang, Renjie , Li, Huimin , Ji, Qiang , Cheng, Xiaomin , Thorne, Rick Francis , Hondermarck, Hubert , Liu, Xiaoying , Shen, Cailiang
- Resource Type: journal article
- Date: 2021
Low tumour-infiltrating lymphocyte density in primary and recurrent glioblastoma
- Creator: Maddison, Kelsey , Graves, Moira C. , Bowden, Nikola A. , Fay, Michael , Vilain, Ricardo E. , Faulkner, Sam , Tooney, Paul A.
- Resource Type: journal article
- Date: 2021
miR-518f-5p decreases tetraspanin CD9 protein levels and differentially affects non-tumourigenic prostate and prostate cancer cell migration and adhesion
- Creator: Bond, Danielle R. , Naudin, Crystal , Carroll, Adam P. , Goldie, Belinda J. , Brzozowski, Joshua S. , Jankowski, Helen M. , Cairns, Murray J. , Ashman, Leonie K. , Scarlett, Christopher J. , Weidenhofer, Judith
- Resource Type: journal article
- Date: 2018
BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma
- Creator: Liu, Fen , Jiang, Chen Chen , Thorne, Rick F. , Jin, Lei , Wang, Qi , Zhang, Xu Dong , Yan, Xu Guang , Tseng, Hsin-Yi , Wang, Chun Yan , Zhang, Yuan Yuan , Yari, Hamed , La, Ting , Farrelly, Margaret , Guo, Su Tang
- Resource Type: journal article
- Date: 2017
A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner
- Creator: Sutton, Selina K. , Carter, Daniel R. , McArthur, Grant A. , Cheung, Belamy B. , Marshall, Glenn M. , Kim, Patrick , Tan, Owen , Arndt, Greg M. , Zhang, Xu Dong , Baell, Jonathan , Noll, Benjamin D. , Wang, Shudong , Kumar, Naresh
- Resource Type: journal article
- Date: 2016
Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors
- Creator: Smith, Amanda M. , Dun, Matthew D. , Toop, Hamish , Lock, Richard B. , Powell, Jason A. , Thomas, Daniel , Guthridge, Mark A. , Moore, Andrew , Ashman, Leonie K. , Skelding, Kathryn A. , Enjeti, Anoop , Verrills, Nicole M. , Lee, Erwin M. , Harrison, Celeste , Kahl, Richard , Flanagan, Hayley , Panicker, Nikita , Mashkani, Baratali , Don, Anthony S. , Morris, Jonathan
- Resource Type: journal article
- Date: 2016
Identification of the microRNA networks contributing to macrophage differentiation and function
- Creator: Zhou, Hong , Zhang, Jie , Eyers, Fiona , Xiang, Yang , Herbert, Cristan , Tay, Hock L. , Foster, Paul S. , Yang, Ming
- Resource Type: journal article
- Date: 2016
ProNGF is a potential diagnostic biomarker for thyroid cancer
- Creator: Faulkner, Sam , Roselli, Severine , Demont, Yohann , Pundavela, Jay , Choquet, Genevieve , Leissner, Philippe , Oldmeadow, Christopher , Attia, John , Walker, Marjorie M. , Hondermarck, Hubert
- Resource Type: journal article
- Date: 2016
Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922
- Creator: Wang, Chun Yan , Guo, Su Tang , Jin, Lei , Zhang, Xu Dong , Jiang, Chen Chen , Wang, Jia Yu , Yan, Xu Guang , Farrelly, Margaret , Zhang, Yuan Yuan , Liu, Fen , Yari, Hamed , La, Ting , Lei, Fu Xi
- Resource Type: journal article
- Date: 2016
The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs
- Creator: Liu, Pei Y. , Sokolowski, Nicholas , Liu, Bing , Yang, Rui H. , Guo, Xiang Y. , Tee, Andrew E. , Itoh, Ken , Wang, Jenny , Kavallaris, Maria , Haber, Michelle , Norris, Murray D. , Cheung, Belamy B. , Guo, Su T. , Byrne, Jennifer A. , Ziegler, David S. , Marshall, Glenn M. , Dinger, Marcel E. , Codd, Rachel , Zhang, Xu D. , Liu, Tao , Siddiqi, Faraz , Atmadibrata, Bernard , Telfer, Thomas J. , Sun, Yuting , Zhang, Lihong , Yu, Denise , Mccarroll, Joshua
- Resource Type: journal article
- Date: 2016
Sortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasion
- Creator: Roselli, Séverine , Pundavela, Jay , Demont, Yohann , Faulkner, Sam , Keene, Sheridan , Attia, John , Jiang, Chen Chen , Zhang, Xu Dong , Walker, Marjorie M. , Hondermarck, Hubert
- Resource Type: journal article
- Date: 2015
Chemosensitization of solid tumors by inhibition of Bcl-xL expression using DNAzyme
- Creator: Yu, Xiaohui , Yang, Lifang , Cairns, Murray J. , Dass, Crispin , Saravolac, Edward , Li, Xiong , Sun, Lun-Quan
- Resource Type: journal article
- Date: 2014
Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1
- Creator: Shahbazi, Jeyran , Scarlett, Christopher J. , Lock, Richard B. , Liu, Tao , Norris, Murray D. , Liu, Bing , Haber, Michelle , Tee, Andrew E. , Carrier, Alice , Biankin, Aandrew V. , London, Wendy B. , Marshall, Glenn M.
- Resource Type: journal article
- Date: 2014
Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells
- Creator: Liu, Yi Lun , Lai, Fritz , Jin, Lei , Zhang, Xu Dong , Wilmott, James S. , Yan, Xu Guang , Liu, Xiao Ying , Luan, Qi , Guo, Su Tang , Jiang, Chen Chen , Tseng, Hsin-Yi , Scolyer, Richard A.
- Resource Type: journal article
- Date: 2014